At sufficient doses (400-600 mg), CBD can alleviate situational anxiety, such as public speaking. Interestingly, cannabis cultivars, or strains, that are high in CBD and low in THC are better than other cultivars for alleviating depression. But when used over a long period of time, any kind of cannabis could make depression worse.  Although clinical trials in people haven’t yet been completed, there is very compelling “petri dish” evidence that CBD can reduce inflammation, for painful conditions such as Crohn’s disease, and fight some cancerous tumors. There is a massive amount of scientific research being done on CBD right now, and we are likely to see many medical breakthroughs in the next decade.
It is well known that people who consume cannabis in other forms notice increased appetite, famously called “the munchies”. However, cannabis essential oil can help regulate your appetite and induce hunger, while also stimulating your digestive system to operate at a regular level. This can help people who want to gain weight quickly, particularly after an extended illness or injury.
^ Tohen, Mauricio; Zarate Jr, Carlos A.; Hennen, John; Khalsa, Hari-Mandir Kaur; Strakowski, Stephen M.; Gebre-Medhin, Priscilla; Salvatore, Paola; Baldessarini, Ross J. (2003). "The McLean-Harvard First-Episode Mania Study: Prediction of Recovery and First Recurrence". American Journal of Psychiatry. 160 (12): 2099–107. doi:10.1176/appi.ajp.160.12.2099. PMID 14638578.
There are concerns that a handful of less-than-reputable companies are tarnishing the industry as a whole. For years, the FDA has been sending warning letters to companies selling CBD while making unsubstantiated health claims. According to the FDA, one company had claimed on its website, “Scientific research by doctors have shown it (CBD) actually kills cancer cells and provides a protective coating around our brain cells.”
That leaves those touting CBD’s effectiveness pointing primarily to research in mice and petri dishes. There, CBD (sometimes combined with small amounts of THC) has shown promise for helping pain, neurological conditions like anxiety and PTSD, and the immune system—and therefore potentially arthritis, diabetes, multiple sclerosis, cancer, and more.
But that’s exactly what happened. According to current federal law, cannabis is considered hemp – not marijuana – as long as no part of the plant (including the leaves and flowers) exceeds a THC concentration of “more than 0.3 percent on a dry weight basis.” Any plant that tops 0.3 percent THC is considered marijuana and is therefore federally illegal to grow, according to Uncle Sam.
Cannabis company Tilray also recently signed a $100 million deal with Authentic Brands Group, whose portfolio includes Juicy Couture, Nine West and Jones New York, to develop and distribute cannabis products. Initially that will mean (hemp-derived) CBD items such as foot creams and mints sold in retail stores and malls across the country. Companies like Constellation Brands, makers of Corona beer, and tobacco giant Altria are also getting into the CBD game with billion-dollar investments.
DEA actions have caused “somewhat of a chill in the industry,” said Miller. Not that he's too worried. “The fact of the matter is, (the DEA) have not done any enforcement actions and we believe they never will,” he said. “The instant that the DEA ever seizes a product that was sold on a shelf somewhere that was a Farm Bill product, the next day, we’re going to be in federal court suing them.”

....but it sure isn't the only game in town. Tip of the hat to you for seeing the coming 'fad" of CBD wellness. But like many of the folks who genuflect at the altar of FDA approval you missed the fact that the teeming masses you see from your ivory tower will believe what they see with their own two eyes. It isn't going to need advertising other than word of mouth.


Irie Hemp will be offering their products for sale in medical marijuana dispensaries in states such as California and Oregon, and as such, all products MUST undergo testing procedures required by the medical marijuana industry. Irie Hemp Company therefore will be adhering to a higher standard than most of the companies currently marketing and selling unregulated hemp based CBD online.

The earliest citing of mental disorders in India are from Vedic Era (2000 BC – AD 600).[98] Charaka Samhita, an ayurvedic textbook believed to be from 400–200 BC describes various factors of mental stability. It also has instructions regarding how to set up a care delivery system.[99] In the same era In south India Siddha was a medical system, the great sage Agastya, one of the 18 siddhas contributing to a system of medicine has included the Agastiyar Kirigai Nool, a compendium of psychiatric disorders and their recommended treatments.[100] In Atharva Veda too there are descriptions and resolutions about mental health afflictions. In the Mughal period Unani system of medicine was introduced by an Indian physician Unhammad in 1222.[101] Then existed form of psychotherapy was known then as ilaj-i-nafsani in Unani medicine.


In response to the FDA’s historic decision, the Drug Enforcement Administration (DEA) announced in September 2018 that it had removed Epidiolex from Schedule I classification, a category reserved for dangerous drugs with no medical value. Henceforth, Epidiolex would be considered a Schedule V drug, the least dangerous designation under the Controlled Substances Act.
Electroconvulsive therapy, insulin shock therapy, lobotomies and the "neuroleptic" chlorpromazine came to be used by mid-century. In the 1960s there were many challenges to the concept of mental illness itself. These challenges came from psychiatrists like Thomas Szasz who argued that mental illness was a myth used to disguise moral conflicts; from sociologists such as Erving Goffman who said that mental illness was merely another example of how society labels and controls non-conformists; from behavioural psychologists who challenged psychiatry's fundamental reliance on unobservable phenomena; and from gay rights activists who criticised the APA's listing of homosexuality as a mental disorder. A study published in Science by Rosenhan received much publicity and was viewed as an attack on the efficacy of psychiatric diagnosis.[128] 

Mental illnesses are more common than cancer, diabetes or heart disease. Over 26 percent of all Americans over the age of 18 meet the criteria for having a mental illness.[18] A WHO report estimates the global cost of mental illness at nearly $2.5 trillion (two-thirds in indirect costs) in 2010, with a projected increase to over $6 trillion by 2030.[citation needed]
All human rights oriented mental health laws require proof of the presence of a mental disorder as defined by internationally accepted standards, but the type and severity of disorder that counts can vary in different jurisdictions. The two most often utilized grounds for involuntary admission are said to be serious likelihood of immediate or imminent danger to self or others, and the need for treatment. Applications for someone to be involuntarily admitted usually come from a mental health practitioner, a family member, a close relative, or a guardian. Human-rights-oriented laws usually stipulate that independent medical practitioners or other accredited mental health practitioners must examine the patient separately and that there should be regular, time-bound review by an independent review body.[156] The individual should also have personal access to independent advocacy.

In the current market space is there much difference in cost, in bulk, between 99+% pure CBD from the different sources being discussed? IOW between high-cbd cannabis, and low-total-cannabinoid “industrial hemp”, and hemp grown for seeds not fiber? Extraction from high-cbd cannabis would seem easier as you have to work with less plant material per unit of end product, but then it costs a lot less per lb plant material to grow a huge field of hemp. So, how does it land these days?
^ Demyttenaere, K; Bruffaerts, R; Posada-Villa, J; Gasquet, I; Kovess, V; Lepine, JP; Angermeyer, MC; Bernert, S; et al. (2 June 2004). "WHO World Mental Health Survey Consortium. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Survey". Journal of the American Medical Association. 291 (21): 2581–2590. doi:10.1001/jama.291.21.2581. PMID 15173149.
Ancient civilizations described and treated a number of mental disorders. Mental illnesses were well known in ancient Mesopotamia,[123] where diseases and mental disorders were believed to be caused by specific deities.[124] Because hands symbolized control over a person, mental illnesses were known as "hands" of certain deities.[124] One psychological illness was known as Qāt Ištar, meaning "Hand of Ishtar".[124] Others were known as "Hand of Shamash", "Hand of the Ghost", and "Hand of the God".[124] Descriptions of these illnesses, however, are so vague that it is usually impossible to determine which illnesses they correspond to in modern terminology.[124] Mesopotamian doctors kept detailed record of their patients' hallucinations and assigned spiritual meanings to them.[123] The royal family of Elam was notorious for its members frequently suffering from insanity.[123] The Greeks coined terms for melancholy, hysteria and phobia and developed the humorism theory. Mental disorders were described, and treatments developed, in Persia, Arabia and in the medieval Islamic world.
Chronic pain: The body’s ECS plays a role in alleviating and managing pain, so CBD oil can work as a supplement for individuals with medical conditions that cause chronic pain, such as arthritis and multiple sclerosis. CBD oil also increases levels of adenosine in the brain; adenosine is a neurotransmitter that aids cardiovascular function and eases painful inflammation.
The base of so many great cannabis products starts with great cannabis oil. At Caliva, we invest in innovation and utilize cutting-edge oil extraction and refinement technology to to produce high purity cannabis oil. Our team of cultivators, scientists, and artisan formulators work together to produce the perfect oil blend to fit your product development needs. From vape cartridges, to specialty topicals, edibles and tincture, our oil formulations serve as the basis for high quality cannabis products. All Caliva oils are tested to 2018 California state standards. Our oil is sold by the kilo only and shipped in laboratory grade glass. 
Irie Hemp Company are sourcing their base extract from whole plant organic Oregon grown, full spectrum high CBD hemp varietals grown specifically for CBD extraction. The farm they are sourcing from in Oregon, is growing hemp under the Oregon Department of Agriculture hemp program and this hemp is being grown SPECIFICALLY for high CBD concentrations. The resultant whole plant extract is a blend of the buds and leaves of the hemp plant, rich in natural phytocannabinoids and terpenes.

Understanding CBD’s analgesic, or pain-relieving, interactions with the ECS can shed light on CBD’s other interactions and effects. Importantly, the ECS participates in our bodies’ pain processing, but when CBD is introduced to our ECS, it stops the body from absorbing a pain-regulating compound known as anandamide — one of our body’s’ own natural cannabinoid molecules. Inhibiting the absorption of this compound shunts excess quantities into the bloodstream that in turn reduces pain. One study has revealed that CBD targets alpha-3 (α3) glycine receptors to suppress chronic pain and inflammation associated with dysfunctional glycine receptors, which are an important target for pain processing in the spine. In both humans and animal models, CBD has been shown to have a variety of anti-inflammatory properties.
As the CBD movement continues to grow, we are very optimistic that both hemp-derived and marijuana-derived CBD will be completely legal in all 50 states within the next 5 years. Of course, it is still very hard to predict the future, especially given the constantly shifting political landscape, but we can continue to push forward, build awareness, and educate the world about the benefits of CBD.
I am a competitive athlete, and so need to be mobile. I am now in desperate search for a high concentration of CBD oil that I can massage directly into my muscles rather than paying an outrageous amount of money for someone to blend together with coconut oil and menthol into a topical cream and put into a deceptive container(the container has a smaller container inside that contains the actual cream so you are getting half the amount that you think you are getting from looking at the container). The trouble is... the stuff works.
The ACMPR requires that all Licensed Producers display total levels of potential THC and CBD on their product labels. Total potential THC is the total amount of THC available when all THCa (tetrahydrocannabinolic acid) is decarboxylated. Total potential CBD is the total of CBD available when all the CBDa (Cannabidiolic acid) is decarboxylated. Learn more about decarboxylation here.
^ Jump up to: a b c d Boggs, Douglas L; Nguyen, Jacques D; Morgenson, Daralyn; Taffe, Michael A; Ranganathan, Mohini (6 September 2017). "Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol". Neuropsychopharmacology. 43 (1): 142–154. doi:10.1038/npp.2017.209. ISSN 0893-133X. PMC 5719112. PMID 28875990.
Buying online is less reliable still because there’s no regulation or standardization. What you see on the label may not be what you are getting. A 2017 study in JAMA found that of the 84 CBD products researchers bought online, 43% had more CBD than indicated, while 26% had less, and some had unexpected THC. “There’s a 75% chance of getting a product where the CBD is mislabeled,” says Marcu, one of the study’s coauthors.
Hemp being federally legal would be huge for the CBD industry, as CBD oil made from hemp extract (a plant that has very low amounts of THC) would be legal. A new, more available form of CBD would also allow for more research on the subject of cannabidiol, and perhaps the entire marijuana plant. More research brings the potential of coming closer to full legalization.
Does Amazon sell CBD oil? Yes. You can also find cannabis oil for sale online via Amazon, though this tends to change from month to month over the last 4 years now.  There used to be a time where you could purchase many of the brands profiled in our merchant stores such as Charlotte's Web on Amazon, but Amazon has since permanently removed merchants who had used the term "CBD" in their labeling. Consequently, to find CBD online via Amazon, you will be first searching for "hemp oil" products, and then filtering out the hempseed oil from the CBD rich hemp extracts. Terms such as "full spectrum" and "whole plant" are commonly used to distinguish these hemp products on Amazon in 2019. 

It is not always clear when a problem with mood or thinking has become serious enough to be a mental health concern. Sometimes, for example, a depressed mood is normal, such as when a person experiences the loss of a loved one. But if that depressed mood continues to cause distress or gets in the way of normal functioning, the person may benefit from professional care. Family or friends may recognize changes or problems that a person doesn’t see in themselves.
We are committed to bringing our customers the highest-grade organic cannabis oil products on the market. Our CBD oil is derived from organic hemp plants and is legal in all 50 states. We proudly call ourselves NuLeaf “Naturals” because our cannabis oils are 100% organic, free of additives and preservatives. Every bottle of cannabis oil we provide to our customers has been subjected to rigorous laboratory testing to ensure that it contains the optimal amount of CBD.
Michael Klein, CEO of platform CannabisMD, said consumer interest is driving the explosion and “with that comes a lot of misinformation, a lot of myth-busting has to be done around it. A barrier for a brand is exactly that—when consumer adoption has outpaced the ability for there to be an authoritative voice that can cut through the clutter for consumers.”
^ Jeronimus B.F.; Kotov, R.; Riese, H.; Ormel, J. (2016). "Neuroticism's prospective association with mental disorders halves after adjustment for baseline symptoms and psychiatric history, but the adjusted association hardly decays with time: a meta-analysis on 59 longitudinal/prospective studies with 443 313 participants". Psychological Medicine. 46 (14): 2883–2906. doi:10.1017/S0033291716001653. PMID 27523506.
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