Transparency was certainly a challenge and a major focus for beauty brand Kiehl’s when it decided to launch a cannabis sativa seed oil designed to reduce facial redness and calm skin. “Many of our customers have heard about cannabis in beauty products, and are eager to try it with a brand that they already use and trust,” said Megan Grant, U.S. brand president, Kiehl’s, adding it’s important to be transparent about how the different types of cannabis ingredients are used in a variety of ways. For Kiehl’s, that means communicating the benefits of cannabis sativa seed oil for skin care.
^ Tanielian, Terri; Hansen, Michael L.; Martin, Laurie T.; Grimm, Geoffrey; Ogletree, Cordaye (2016). "CHAPTER FOUR Available Mental Health Support Services and Resources". Supporting the Mental Health Needs of Veterans in the Metro Detroit Area. Supporting the Mental Health Needs of Veterans in the Metro Detroit Area. pp. 41–58. doi:10.7249/j.ctt19w7343.9 (inactive 2019-02-15). JSTOR 10.7249/j.ctt19w7343.9.
The terms "mental breakdown" or "nervous breakdown" may be used by the general population to mean a mental disorder. The terms "nervous breakdown" and "mental breakdown" have not been formally defined through a medical diagnostic system such as the DSM-5 or ICD-10, and are nearly absent from scientific literature regarding mental illness. Although "nervous breakdown" is not rigorously defined, surveys of laypersons suggest that the term refers to a specific acute time-limited reactive disorder, involving symptoms such as anxiety or depression, usually precipitated by external stressors. Many health experts today refer to a nervous breakdown as a "modern mental health crisis".
A survey led by the McGill University Health Centre in Canada revealed that cannabis use results in an improvement in non-cancer pain, sleep, and mood patterns. In the same survey, it also revealed that ‘high’ and dry mouth were the most commonly reported side effects. People who suffer from cancer also turn to cannabis-related options, including therapeutic grade CBD oil, when the pain of chemotherapy or the disease itself becomes unbearable.
^ Sellers, R.; Collishaw, S.; Rice, F.; Thapar, A.K.; Potter, R.; Mars, B.; Harold, G.T.; Smith, D.J.; Owen, M.J.; Craddock, N.; Thapar, A. (2012). "Risk of psychopathology in adolescent offspring of mothers with psychopathology and recurrent depression". The British Journal of Psychiatry. 202 (2): 108–14. doi:10.1192/bjp.bp.111.104984. PMID 23060622.
In the past several years however, public interest in CBD has skyrocketed based on claims — largely unsubstantiated through good clinical research thus far — that it may be a kind of cure-all miracle drug, with therapeutic effects ranging from pain relief to eradicating cancer. In fact, while CBD research has been limited due to federal restrictions, preliminary evidence does suggest that it might help with psychiatric conditions like anxiety disorders (note that while many people claim that CBD is not “psychoactive,” it’s potential as an anxiolytic medication suggests otherwise) and recent randomized, controlled clinical trials suggest a possible role in the treatment of psychotic disorders.2,3 In 2018, the Food and Drug Administration (FDA) approved Epidiolex, a form of CBD manufactured by GW Pharmaceuticals, for the treatment of rare forms of pediatric epilepsy (see my blogpost "Cannabis for Kids: Can Marijuana Treat Childhood Seizures?").
The use of drugs (legal or illegal, including alcohol), when it persists despite significant problems related to its use, may be defined as a mental disorder. The DSM incorporates such conditions under the umbrella category of substance use disorders, which includes substance dependence and substance abuse. The DSM does not currently use the common term drug addiction, and the ICD simply refers to "harmful use". Disordered substance use may be due to a pattern of compulsive and repetitive use of the drug that results in tolerance to its effects and withdrawal symptoms when use is reduced or stopped.
A wide variety of solvents can be used for extraction, such as chloroform, dichloromethane, petroleum ether, naphtha, benzene, butane, methanol, ethanol, isopropanol, and olive oil. Currently, resinoids are often obtained by extraction with supercritical carbon dioxide. The alcohols extract undesirable water-soluble substances such as chlorophylls and sugars (which can be removed later by washing with water). Non-polar solvents such as benzene, chloroform and petroleum ether will not extract the water-soluble constituents of marijuana or hashish while still producing hash oil. In general, non-polar cannabis extracts taste much better than polar extracts. Alkali washing further improves the odor and taste.
CBD has some other very important jobs outside of the endocannabinoid system (ECS). For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A), which may explain CBD’s effects on depression and anxiety. It also acts at the peroxisome proliferator activated receptors (PPARs), which halt the proliferation of cancer cells and convey neuro- and cardioprotection. By interacting with a particular PPAR (gamma), CBD could prove to be a promising new way to prevent alzheimer’s disease and other brain disorders.