I bought some CBD oil from a quality pet store to try on our senior Chihuahua. He has arthritis and a bad heart murmur. At first it really seemed to help with his pain and he was much more mobile. After a few weeks he started getting more lethargic and not eating. I did some research and discovered it should not be given along with any medications that are metabolized by the liver. It causes these meds to build up in the body so he was exhibiting symptoms of overdose of his heart medications. I stopped the CBD oil and he got started eating and seemed to feel better. Give with caution if your pet is on other meds.

^ Collins, Pamela Y.; Patel, Vikram; Joestl, Sarah S.; March, Dana; Insel, Thomas R.; Daar, Abdallah S.; Bordin, Isabel A.; Anderson, E. Jane; Dhansay, Maureen; Phillips, Christopher; Shurin, Roger I.; Walport, Wayne; Ewart, Yueqin; Savill, Steven E.; Bordin, Kay; Costello, Sylvia; Durkin, Shitij; Fairburn, Arthur; Glass, Adesola; Hall, Angel; Huang, Mu-Ming; Hyman, Vijayalakshmi; Jamison, Barbara J.; Kaaya, Shekhar; Kapur, Peter A.; Kleinman, Dan J.; Ogunniyi, Warwick; Otero-Ojeda, Muhammad A.; Poo, Wendy; Ravindranath, Anthony; Scientific Advisory Board the Executive Committee of the Grand Challenges on Global Mental Health (2011). "Grand challenges in global mental health". Nature. 475 (7354): 27–30. doi:10.1038/475027a. PMC 3173804. PMID 21734685.
According to the World Health Organization in 2004, depression is the leading cause of disability in the United States for individuals ages 15 to 44.[118] Absence from work in the U.S. due to depression is estimated to be in excess of $31 billion per year. Depression frequently co-occurs with a variety of medical illnesses such as heart disease, cancer, and chronic pain and is associated with poorer health status and prognosis.[119] Each year, roughly 30,000 Americans take their lives, while hundreds of thousands make suicide attempts (Centers for Disease Control and Prevention).[120] In 2004, suicide was the 11th leading cause of death in the United States (Centers for Disease Control and Prevention), third among individuals ages 15–24. Despite the increasingly availability of effectual depression treatment, the level of unmet need for treatment remains high.[citation needed] By way of comparison, a study conducted in Australia during 2006 to 2007 reported that one-third (34.9%) of patients diagnosed with a mental health disorder had presented to medical health services for treatment.[121]

In 2014, the Alabama state legislature passed SB 174, a restrictive cannabidiol (CBD) law. Officially entitled "Carly's Law," it offers an affirmative defense for the possession and use of CBD; however, the program is extremely limited and may not be able to provide CBD-rich medicine to patients in Alabama. In 2016, HB 61 was passed, which expanded the affirmative defense to several conditions and removed the requirement that patients must be enrolled in the UAB study program.
Many a time, multiple cannabinoid compounds are used together, either knowingly or unknowingly.  It is, hence, tough to discern the extent to which each compound is involved in causing the desired effect. There are cases where a group of cannabinoids works synergistically in bringing about bodily reactions. Studies selectively employing CBD oil are few in number, but promising.
In order to create a system where oils can be provided to patients when the original prescription is expressed in grams of dried product, each Licensed Producer must provide an ‘Equivalency Factor’. This allows you to see how much oil you can purchase to be in line with your prescription and ensures that you do not go over your prescribed allowance. For example, a 60ml bottle of Blueberry Lamsbread Cannabis Oil, which has an equivalency factor of 12 ml of oil to 1 gram of dried cannabis, will use 5 grams of your possession limit.
Psychopathology has generally been traced, at least in captivity, to adverse rearing conditions such as early separation of infants from mothers; early sensory deprivation; and extended periods of social isolation. Studies have also indicated individual variation in temperament, such as sociability or impulsiveness. Particular causes of problems in captivity have included integration of strangers into existing groups and a lack of individual space, in which context some pathological behaviors have also been seen as coping mechanisms. Remedial interventions have included careful individually tailored re-socialization programs, behavior therapy, environment enrichment, and on rare occasions psychiatric drugs. Socialization has been found to work 90% of the time in disturbed chimpanzees, although restoration of functional sexuality and care-giving is often not achieved.[192][195]
Thank you for your response. It is still not clear to me. Tricky is an understatement. It appears that it was the DEA that put it on schedule 1 in Dec. 2016, and per legal precedent from the DEA's previous loss at the same effort, in the "Hemp Industries Association v. DEA" legal case 14 years ago, it is being challenged again? The FDA also just closed a consumer comment request on 9/13/17 in collaboration with the UN/WHO review on CBD and the FDA acknowledged it is on Schedule 1, they stated it was the only "beneficial" substance on the list under review.
In addition to CBD, Cannabis sativa L contains organic compounds called terpenes. Terpenes are isomeric hydrocarbons (C10H16) used to create essential oils, balsams, and other by-products. When chemically modified through oxidation or other methods, terpenes become terpenoids (sometimes referred to as isoprenoids). Vitamin A is one example of a terpenoid.
I am a chronic pain patient who lives in NYS. I have been suffering with this condition for 7 years. I am now legally registered for medical marijuana. I only take CBD products, because I don't like how the THC makes me feel. While expensive, it provides significant relief, better than any of my prescription drugs do. I highly recommend that anyone with Chronic Pain Syndrome consider going through the relatively easy evaluation process so that you can try products currently legally on the market.
The next big challenge, provided the new bill passes, will be regulation, which leaders in the industry hope they’ll be able to do themselves. Miller told me they’re setting up a self-regulating organization, like other agriculture commodities have, to set best-practice standards and uniform quality control. “This will give consumers assurance that the product is safe, and it gives law enforcement assurance that the product’s legal,” he said.
I suffer from incredible pain relating to a Celiac artery surgery that left me with a 19 in scar around my waist. The pain is along, above and below the scar area. I take 5 Percocets 10/325 daily, one every 4.5 hours. In Az medical marijuana is legal with a card from a physician. I tried Vital Tincture oil CBD 100 under the tongue. I didn't see any relief with it. On a recommendation I tried a Vape Pen with CBD oil from my local dispensaries. I get instant relief for anywhere between a half and hour to a couple of hours. When I'm awaken in the morning from pain, I take 2 puffs from the Vape Pen and one Percocet. My pain is reduced substantially while waiting for the pain pill to take effect. I'm NOT recommending anything here, just letting you know how it helps me. By the way, I'm 71 and have been with this pain for over 5 years since the surgery. I've had CT, CT with contrast, MRI etc and nothing irregular was ever found from the surgery. 

We have been involved in Colorado's medicinal and legal cannabis industry since its inception, so we've seen the expansion from high quality medicine to social commodity. Investment dollars have rushed into various sectors of the industry and the primary focus is ROI. When people see green it's easy to get excited and focus on the numbers instead of the patients. Of all the companies we've interacted with and tested, Ambary Gardens has been the standout. Their vertically integrated Colorado-based facility is is impressive as their product line.
According to the case report, it was charted by the girl’s oncologist that the patient “suffers from terminal malignant disease. She has been treated to the limits of available therapy … no further active intervention will be undertaken.” She was then placed in a palliative home care and told to prepare for her disease to overwhelm her body. She was expected to suffer a stroke within the next two months.
The side effects and risks involved with consuming marijuana-based products aren't clear, either, Bonn-Miller said. It's important to "determine cannabinoids that are useful therapeutically while understanding and using cannabinoids that are associated with less risk," he said. At least with CBD, he said, it doesn't appear to have the potential for addiction. That's different from THC, which has been associated with addiction, he said, and negative side effects, including acute anxiety.

At sufficient doses (400-600 mg), CBD can alleviate situational anxiety, such as public speaking. Interestingly, cannabis cultivars, or strains, that are high in CBD and low in THC are better than other cultivars for alleviating depression. But when used over a long period of time, any kind of cannabis could make depression worse.  Although clinical trials in people haven’t yet been completed, there is very compelling “petri dish” evidence that CBD can reduce inflammation, for painful conditions such as Crohn’s disease, and fight some cancerous tumors. There is a massive amount of scientific research being done on CBD right now, and we are likely to see many medical breakthroughs in the next decade.

The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.
Services are based in psychiatric hospitals or in the community, and assessments are carried out by mental health professionals such as psychiatrists, psychologists, and clinical social workers, using various methods such as psychometric tests but often relying on observation and questioning. Treatments are provided by various mental health professionals. Psychotherapy and psychiatric medication are two major treatment options. Other treatments include lifestyle changes, social interventions, peer support, and self-help. In a minority of cases there might be involuntary detention or treatment. Prevention programs have been shown to reduce depression.[6][8]
One of the most profound uses of cannabidiol oil is for the relief of arthritic pain. There are two kinds of arthritis, rheumatoid and osteoarthritis, both resulting in swelling and stiffness in joints.  Scientific studies have documented that the application of CBD oil can help assuage the pain caused by inflammations. Results have been encouraging. Health associations and the government, alike, are optimistic about the role of CBD oil in bringing solace to arthritic patients.

Psychiatric social workers conduct psychosocial assessments of the patients and work to enhance patient and family communications with the medical team members and ensure the inter-professional cordiality in the team to secure patients with the best possible care and to be active partners in their care planning. Depending upon the requirement, social workers are often involved in illness education, counseling and psychotherapy. In all areas, they are pivotal to the aftercare process to facilitate a careful transition back to family and community. [88]
In June 2014, the New York Assembly passed S7923, which creates legal protections for patients and caregivers and authorizes the state to license and regulate “registered organizations” to cultivate and sell medical cannabis to patients. Patients must obtain a registration identification card after getting written certification from their physician.
Bluebird CBD products and extracts are derived from hemp (not marijuana), and can also be referred to as CBD hemp oil, hemp-derived CBD oil, or plainly “hemp extracts,” since they typically contain more than just CBD. However, CBD oil is different from hemp seed oil and organic hemp oil, as these are derived from hemp seeds (not the resin) and do not contain cannabidiol.
Some states offer cannabis for medical conditions, and this may require a medical note or proof of injury and illness. You can also join a collective, which is a group of patients who grow and share medical cannabis with each other. If you are using cannabis oil, it’s so important to make sure it’s purchased through a reputable company that sells pure and lab-tested oils. If you’re wondering how to make cannabis oil, you should first make sure this is legal in your state. Some people also like to make cannabis coconut oil, which is basically cannabis-infused coconut oil.
Online retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
Still, Blessing notes, amounts below 100 milligrams haven’t even been tested, so it’s not impossible that small amounts may have some effects. As far as anyone knows, heating up CBD doesn’t degrade its effects, and early evidence suggests that taking it along with high-fat food (like a dessert) aids the body’s absorption of the chemical. Beyond that, all anyone has is guesswork. By Chloe didn’t respond to a detailed list of questions about its sourcing and dosing, but I tried a few of the company’s CBD treats anyway. They were all incredibly tasty, and after consuming three cookies in the course of 24 hours, I accidentally fell asleep on my couch at an indeterminate time of the evening and woke up at 4:30 in the morning. Was it the CBD, or was I just tired? Maybe it was a classic placebo effect, in which I expected to be relaxed and became so.
The relationship between THC and CBD is complex, but in short, CBD appears to minimize some of THC’s undesirable effects, such as paranoia, heart palpitations, and impaired thinking. Compared with THC in isolation, or its synthetic cousins such as Marinol, the combination of THC and CBD has much greater therapeutic value to patients. This phenomenon of cannabis-derived molecules working better together than they do in isolation is commonly referred to as the entourage effect.

“This bill will help get sick children potentially life-changing medicine. By crafting the legislation in a way that allows for tightly controlled medical studies, we can ensure we are researching possible treatments in a responsible and scientific way. The CBD oil we are studying is a non-intoxicating derivative of marijuana. It is not marijuana, and it is not anything that can make you ‘high.’ This law has been narrowly crafted to support highly supervised medical trials for children with debilitating seizures. It is not a first step towards legalizing marijuana, and I will never support the legalization of marijuana in Oklahoma.”
Women's College Hospital is specifically dedicated to women's health in Canada. This hospital is located in downtown Toronto where there are several locations available for specific medical conditions. WCH is an organization that helps educate women on mental illness due to its specialization with women and mental health. The organization helps women who have symptoms of mental illnesses such as depression, anxiety, menstruation, pregnancy, childbirth, and menopause. They also focus on psychological issues, abuse, neglect and mental health issues from various medications.[116]
Since the 1980s, Paula Caplan has been concerned about the subjectivity of psychiatric diagnosis, and people being arbitrarily “slapped with a psychiatric label.” Caplan says because psychiatric diagnosis is unregulated, doctors are not required to spend much time interviewing patients or to seek a second opinion. The Diagnostic and Statistical Manual of Mental Disorders can lead a psychiatrist to focus on narrow checklists of symptoms, with little consideration of what is actually causing the patient’s problems. So, according to Caplan, getting a psychiatric diagnosis and label often stands in the way of recovery.[87][unreliable medical source]
Industrial hemp typically contains far less cannabidiol than high-resin CBD-rich cannabis, so a large amount of industrial hemp is required to extract a small amount of CBD. This raises the risk of contaminants as hemp is a “bio-accumulator”— meaning the plant naturally draws toxins from the soil. That’s wonderful for phyto-remedial purposes, but it’s not so great for making ingestible medicinal oil products. Oil extracted from hemp and cannabis will concentrate the toxins as well as the good stuff
Sueki, (2013) carried out a study titled “The effect of suicide–related internet use on users’ mental health: A longitudinal Study”. This study investigated the effects of suicide-related internet use on user’s suicidal thoughts, predisposition to depression and anxiety and loneliness. The study consisted of 850 internet users; the data was obtained by carrying out a questionnaire amongst the participants. This study found that browsing websites related to suicide, and methods used to commit suicide, had a negative effect on suicidal thoughts and increased depression and anxiety tendencies. The study concluded that as suicide-related internet use adversely affected the mental health of certain age groups it may be prudent to reduce or control their exposure to these websites. These findings certainly suggest that the internet can indeed have a profoundly negative impact on our mental health.[37]

Yes, it’s important to remember that a person’s mental health can change over time, depending on many factors.  When the demands placed on a person exceed their resources and coping abilities, their mental health could be impacted. For example, if someone is working long hours,Cdc-pdf caring for an ill relative or experiencing economic hardship they may experience poor mental health.
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
Choosing CBD products isn’t as simple as picking something off the dispensary shelf and then walking out the door. Consumers should be aware that a handful of hemp products on the market pay lip service to governmental regulations by labeling themselves as hemp, despite containing cannabinoids and terpenoids. Some CBD products are completely devoid of cannabinoids including CBD, despite package labeling. The FDA purchased a number of CBD products online in 2015 and 2016 to test them for the presence of CBD and other cannabinoids. They found that the amount of CBD these products claimed on their labels was markedly inaccurate; some didn’t even contain CBD.

It’s pretty easy to tell if recreational marijuana is legal in your state—you can walk into a store and buy it, you drive past 15 pot-leaf billboards on your way to work, and the smell is everywhere. But the legality of cannabidiol, weed’s won’t-get-you-high sibling, is trickier. Wherever you live, CBD (one of the main components of the cannabis plant, along with THC) is likely freely available. It’s on health food store shelves across the country, sold online, and even in pet stores. CBD supplements and oils are being marketed as the latest health and wellness cure—they're purported to have anti-inflammatory properties, calm anxiety, and relieve pain. CBD can be taken orally or used topically, say, to soothe muscle aches, which is the reason Olivia Wilde told the New York Times she uses it.


The American public is starting to see the light when it comes to CBD as a safe and effective treatment option for a long list of medical problems. While THC and similar oils have been used for their health benefits going back to the dawn of civilization (even before the Great Wall of China was built!), people are just recently rediscovering the profound positive impact these oils can have on treating ailments.


^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
CBD has powerful effects on the liver as well. Have you ever had a prescription that warns you not to take the medicine along with grapefruit? That’s because grapefruit inhibits certain drug-metabolizing enzymes in your liver, resulting in much higher levels of your medication in your bloodstream. CBD does the same thing, so it is wise to discuss your medication regimen with a doctor or pharmacist before engaging in CBD therapy.
Marijuana-derived CBD products, on the other hand, don’t enjoy the same luxuries. Because it has been derived from THC-rich marijuana, marijuana-derived CBD, even its isolated from, is considered as a byproduct of marijuana and is judged accordingly. In some states, marijuana-derived CBD is completely legal, while in others, it is completely illegal, but in most states, its a bit of a mixed bag, each state having CBD-specific laws.
REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
The problem is, it’s not easy to know what you’re actually ingesting, or if it’ll actually change how you feel. At best, CBD in America exists in a confusing state of quasi-legality and yet-to-be-realized potential. Experts estimate that the market for it could balloon to $22 billion by 2022, but with cannabis and hemp laws changing rapidly across the country, the chemical is almost entirely unregulated on the consumer market, with no end-product labeling or composition standards to help shoppers understand what they’re buying.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
Relief may come in an unexpected form: Mitch McConnell. The Republican Senate majority leader has introduced new legislation, the Hemp Farming Act of 2018, which would remove hemp from the DEA’s Controlled Substances Act (CSA). It also would allow for commerce, which clears up the confusion and varying interpretations of the 2014 Farm Bill. A vote is slated for this fall.
The most common mental illnesses in children include, but are not limited to, ADHD, autism and anxiety disorder, as well as depression in older children and teens. Having a mental illness at a younger age is much different from having one in your thirties. Children's brains are still developing and will continue to develop until around the age of twenty-five.[32] When a mental illness is thrown into the mix, it becomes significantly harder for a child to acquire the necessary skills and habits that people use throughout the day. For example, behavioral skills don’t develop as fast as motor or sensory skills do.[32] So when a child has an anxiety disorder, they begin to lack proper social interaction and associate many ordinary things with intense fear.[33] This can be scary for the child because they don’t necessarily understand why they act and think the way that they do. Many researchers say that parents should keep an eye on their child if they have any reason to believe that something is slightly off.[32] If the children are evaluated earlier, they become more acquainted to their disorder and treating it becomes part of their daily routine.[32] This is opposed to adults who might not recover as quickly because it is more difficult for them to adapt.

The vast majority of CBD oils come in bottles measuring either 15 milliliters (mL), or 0.5 ounces; or 30 mL, or 1 ounce. However, CBD concentration is more important than bottle size. Concentration refers to the ratio of hemp oil solution (measured in mL) compared to the amount of CBD cannabinoid (measured in milligrams, or mg). A 15-mL bottle may contain 100 mg of CBD, 300 mg, 500 mg, or more. The higher the mg amount, the stronger the CBD oil will be. For this reason, the ‘mg’ measurement is also referred to as the oil’s strength; i.e., 400-mg oil might be called 400-strength oil.


Definitely not. Standard hemp seed oil, which can be found very cheaply at a grocery store, is a much different product than our full-spectrum hemp extracts (not from seed). Standard hemp seed oil is produced by cold pressing the seeds, whereas our hemp extract is a full plant extraction with many components not typically found in the seeds. Hemp seed oil is considered to be a great nutritive food, but it doesn’t have the naturally occurring terpenes, cannabinoids and other components that our extracts do have.
CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
New York Times bestselling author Joel C. Rosenberg has written 13 novels and five nonfiction titles, and has produced multiple documentaries. He has also served as a communications advisor for a number of U.S. and Israeli leaders, and is the founder and chairman of global Christian organization, The Joshua Fund. Drawing on his heritage, depth of studies, and political experience in the Middle East, Joel Rosenberg has crafted numerous gripping thrillers including his upcoming release, The Persian Game.

Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[31] It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12.[12] Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors.[12] In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[32] and this action may be involved in its antidepressant,[33][34] anxiolytic,[34][35] and neuroprotective effects.[36][37] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[38] The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.[7]


Thank you for your response. It is still not clear to me. Tricky is an understatement. It appears that it was the DEA that put it on schedule 1 in Dec. 2016, and per legal precedent from the DEA's previous loss at the same effort, in the "Hemp Industries Association v. DEA" legal case 14 years ago, it is being challenged again? The FDA also just closed a consumer comment request on 9/13/17 in collaboration with the UN/WHO review on CBD and the FDA acknowledged it is on Schedule 1, they stated it was the only "beneficial" substance on the list under review.


Infusions: Research and opportunity have driven chefs and chemists to infuse CBD into all sorts of readily usable products, such as edibles to elixirs, sublingual sprays, capsules and even topicals. Much like concentrates, each infusion sports specific combinations or isolations of CBD, THC, and other cannabinoids, allowing users to pick and choose products that suit their exact needs. CBD topicals, for example, are incredibly effective when applied to surface-level problems like bruises, joint aches, and headaches, and have been scientifically proven to successfully combat skin-based issues including pruritus with far broader implications.
Hash oils seized in the 1970s had a THC contents ranging from 10 to 30%. The oil available on the U.S. West Coast in 1974 averaged about 15% THC.[2] Samples seized across the United States by the Drug Enforcement Administration over an 18-year period (1980–1997) showed that THC content in hashish and hashish oil averaging 12.9% and 17.4%, respectively, did not show an increase over time.[4] The highest THC concentrations measured were 52.9% in hashish and 47.0% in hash oil.[5] Hash oils in use in the 2010s had THC concentrations as high as 90%[6][7] and other products achieving higher concentrations [8]
There are two main types of receptors in the ECS: CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide (named after the Sanskrit term “Ananda,” which translates to “peace”).

Strengthening and supporting children and adults with behavioral health needs through prevention services, community based outpatient services, inpatient chemical dependency, psychiatric hospitalization and services for offenders incarcerated in state correctional facilities. The goal of the continuum of behavioral health services is to foster independent and healthy individuals and families in South Dakota.
The list of states where medical or recreational use of marijuana and CBD is legal keeps growing. Thirty-three states and Washington, D.C., have passed medical marijuana laws (including 10 states and the nation's capital where recreational and medical use is legal), says Paul Armentano, deputy director of the National Organization for the Reform of Marijuana Laws (NORML). Also, 14 states have enacted CBD-explicit medical laws.
Hemp producers who sell CBD products will often use the 2014 Farm Bill to claim that it is legal. This bill includes a provision that allows for the legal cultivation of hemp provided it is used for academic agricultural research or under a state pilot program. But there is still confusion about whether the legal allowance for cultivation also includes selling it.
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